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Kevin E Yarasheski Selected Research

Proteins (Proteins, Gene)

6/2014CNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition.
11/2010Impact of viral-mediated IGF-I gene transfer on skeletal muscle following cast immobilization.
7/2009A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system.
11/2008Evaluation of high-protein supplementation in weight-stable HIV-positive subjects with a history of weight loss: a randomized, double-blind, multicenter trial.
3/2008HIV-protease inhibitors induce expression of suppressor of cytokine signaling-1 in insulin-sensitive tissues and promote insulin resistance and type 2 diabetes mellitus.
6/2007Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates.
7/2006Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo.
11/2004Mechanical ventilation depresses protein synthesis in the rat diaphragm.
10/2003Exercise, aging, and muscle protein metabolism.
9/2003Insulin is protein-anabolic in chronic renal failure patients.
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Kevin E Yarasheski Research Topics

Disease

15Insulin Resistance
01/2019 - 10/2003
11Alzheimer Disease (Alzheimer's Disease)
01/2022 - 07/2006
5Acquired Immunodeficiency Syndrome (AIDS)
01/2019 - 10/2003
5Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2019 - 06/2007
5Infections
01/2019 - 11/2002
5Frailty
12/2016 - 12/2002
4Inflammation (Inflammations)
01/2019 - 06/2007
4Weight Loss (Weight Reduction)
01/2017 - 01/2003
4Hyperinsulinism (Hyperinsulinemia)
07/2015 - 10/2003
4Cardiovascular Diseases (Cardiovascular Disease)
06/2012 - 01/2008
4Dyslipidemias (Dyslipidemia)
12/2006 - 10/2003
3Amyloidosis
01/2022 - 08/2021
3Atherosclerosis
01/2019 - 06/2012
3HIV Infections (HIV Infection)
01/2019 - 12/2011
3Glucose Intolerance
07/2015 - 10/2006
3Type 2 Diabetes Mellitus (MODY)
03/2008 - 04/2005
2Vascular Diseases (Vascular Disease)
07/2015 - 12/2006
2Sarcopenia
03/2011 - 10/2003
2Hypertrophy
11/2010 - 10/2003
2Hyperglycemia
03/2008 - 10/2006
2Hyperlipidemias (Hyperlipidemia)
03/2007 - 08/2004
2Malnutrition (Nutritional Deficiencies)
04/2006 - 06/2004
2Protein-Energy Malnutrition (Marasmus)
04/2006 - 06/2004
1Cognitive Dysfunction
01/2022
1Dementia (Dementias)
01/2022
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2019
1Amyloid Plaque
01/2018
1Pathological Protein Aggregation
02/2016
1Prostatic Neoplasms (Prostate Cancer)
01/2016
1Myocardial Infarction
07/2015
1Stroke (Strokes)
07/2015
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
07/2015
1Viremia
06/2012
1Atherosclerotic Plaque (Atheroma)
06/2012
1Arteritis
06/2012
1Rupture
06/2012
1Nervous System Diseases (Neurological Disorders)
01/2012
1Left Ventricular Dysfunction
12/2011
1Muscular Atrophy (Muscle Atrophy)
11/2010
1Insulinoma
04/2009
1Body Weight (Weight, Body)
05/2007

Drug/Important Bio-Agent (IBA)

11Proteins (Proteins, Gene)FDA Link
06/2014 - 01/2003
10Glucose (Dextrose)FDA LinkGeneric
01/2019 - 12/2005
9Insulin (Novolin)FDA Link
12/2011 - 09/2003
7Amyloid (Amyloid Fibrils)IBA
01/2022 - 07/2006
6Biomarkers (Surrogate Marker)IBA
01/2022 - 03/2011
6Amyloid beta-PeptidesIBA
08/2021 - 07/2006
5LipidsIBA
01/2019 - 10/2003
4Leucine (L-Leucine)FDA Link
10/2006 - 11/2002
3Amino AcidsFDA Link
01/2012 - 09/2003
3Ritonavir (Norvir)FDA Link
04/2009 - 08/2005
3Protease Inhibitors (Protease Inhibitor)IBA
03/2007 - 10/2003
3Muscle Proteins (Muscle Protein)IBA
01/2005 - 10/2003
2ApolipoproteinsIBA
08/2021 - 01/2012
2Pharmaceutical PreparationsIBA
01/2021 - 07/2009
2Sitagliptin Phosphate (Januvia)FDA Link
01/2019 - 07/2015
2Biological ProductsIBA
01/2018 - 11/2008
2IsotopesIBA
07/2015 - 07/2009
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
11/2013 - 01/2011
2Pioglitazone (Actos)FDA Link
11/2013 - 01/2011
2HIV Protease InhibitorsIBA
05/2010 - 03/2008
2Fatty Acids (Saturated Fatty Acids)IBA
05/2010 - 03/2007
2CytokinesIBA
03/2008 - 06/2004
2amprenavir (Agenerase)FDA Link
05/2007 - 08/2005
2GlucocorticoidsIBA
12/2006 - 04/2006
2Hormones (Hormone)IBA
08/2005 - 10/2003
2Myosin Heavy Chains (Myosin Heavy Chain)IBA
11/2004 - 10/2003
1Phosphotransferases (Kinase)IBA
01/2019
1Dipeptidyl-Peptidase IV InhibitorsIBA
01/2019
1ChemokinesIBA
01/2019
1Chloroquine (Aralen)FDA LinkGeneric
01/2019
1Antimalarials (Antimalarial Agents)IBA
01/2019
1PalmitatesIBA
01/2017
1TrehaloseIBA
02/2016
1DisaccharidesIBA
02/2016
1Adenosine Triphosphate (ATP)IBA
01/2016
1NiclosamideFDA Link
01/2016
1Superoxide Dismutase-1IBA
07/2015
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
06/2014
1PPAR gammaIBA
11/2013
1Peptides (Polypeptides)IBA
06/2013
1Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
06/2012
1Apolipoproteins E (ApoE)IBA
01/2012
1Apolipoprotein E4IBA
01/2012
1Apolipoprotein E2IBA
01/2012
1Protein Isoforms (Isoforms)IBA
01/2012
1AdiponectinIBA
01/2011
1Messenger RNA (mRNA)IBA
11/2010
1Insulin-Like Growth Factor I (IGF-1)IBA
11/2010
1tipranavirFDA Link
04/2009
1LopinavirFDA Link
04/2009
1Atazanavir Sulfate (Reyataz)FDA Link
04/2009
1CarbohydratesIBA
11/2008
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
12/2006
1Dexamethasone (Maxidex)FDA LinkGeneric
12/2006
1Fenofibrate (CiL)FDA LinkGeneric
12/2006

Therapy/Procedure

7Therapeutics
12/2016 - 08/2004
7Highly Active Antiretroviral Therapy (HAART)
07/2015 - 10/2003
3Activities of Daily Living (ADL)
11/2005 - 12/2002
1Institutionalization (Institutionalized Persons)
12/2016